Drug Likeness
Below you see a section of an SDFile with the prediction results from PASS. We introduced a new field "DRUG_LIKENESS" that tells you the percentage that your compound is drug like. This one is with 97.9 % probability a drug. The answer is right, the compound is from a group of acetylcholinesterase inhibitors taken from MDDR.
-ISIS- 09190111482D
27 30 0 0 0 0 0 0 0 0999 V2000
-1.7103 1.9897 0.0000 C 0 0 3 0 0 0 0 0 0 0 0 0
-....
26 27 1 0 0 0 0
M END
> <MOLREGNO> (66219)
66219
> <DRUG_LIKENESS>
0.979
> <ACTIVITY_PREDICTION>
45 substructure descriptors; 0 new.
Exclude structure with activities:
Acetylcholinesterase inhibitor
Cholinergic
Cognition disorders treatment
163 of 1043 possible activities at Pa > Pi.
Pa Pi for Activity:
0.869 0.010 Nootropic
0.812 0.018 Antiamyloidogenic
0.768 0.007 Antipa....
